High Glycemic Index and Inflammation

A recent study published in the American Journal of Clinical Nutrition (2010; 92(3): 634-43) further demonstrates the direct relationship between a high glycemic diet and inflammation. In a study involving 1490 postmenopausal women and 1245 men (baseline average age: 49 years) from a population-based cohort, women consuming a diet with the highest glycemic index (highest tertile) were found to have a 2.9-fold increased risk of inflammatory-disease related death, as compared to women in the lowest tertile of GI diet (multivariate HR=2.89). Increased intakes of foods high in refined sugars or starches and decreasing intake of vegetables other than potatoes as well as cereals and breads was also independently associated with a greater risk. The authors conclude, “These data provide new epidemiologic evidence of a potentially important link between GI and inflammatory disease mortality among older women.”

Green Tea and Metabolic Syndrome

Because metabolic syndrome is something I tend to see on a weekly basis, it’s always good to see new information on what can help to control and reverse this condition. The latest research points out the benefits of green tea in treating metabolic syndrome. It’s also well known that green tea contains weight-loss promoting properties, among many other beneficial compounds. 

Here is a summary of the research findings:

Reference: “Green tea minimally affects biomarkers of inflammation in obese subjects with metabolic syndrome,” Basu A, Lyons TJ, et al, Nutrition, 2010 Jun 1; [Epub ahead of print]. (Address: Nutritional Sciences, Oklahoma State University, Stillwater, Oklahoma, USA).
Summary: In a randomized, controlled study involving 35 obese subjects with metabolic syndrome, results indicate that green tea intake may exert cardioprotective benefits. The subjects were randomized to receive green tea (4 cups/d), green tea extract (2 capsules and 4 cups water/d), or no treatment (4 cups water/d) for 8 weeks. At intervention end, green tea (drink and capsule) intake was associated with significant reduction of plasma serum amyloid alpha, compared with control. Thus, the authors of this study conclude, “green tea significantly reduced plasma serum amyloid alpha, an independent cardiovascular disease risk factor, in obese subjects with metabolic syndrome.”

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