Acupuncture, Hot Flashes, and Tamoxifen

The Journal of Complementary and Alternative Medicine published a recent study demonstrating the benefits of acupuncture for treating hot flashes and other side-effects related to chemotherapy and tamoxifen. Patients used in the study had been receiving tamoxifen for at least 6 months, and experiencing at least 4 hot flashes and night sweats per day for at least 3 months. Treatment with acupuncture (8 treatments) was found to reduce the frequency of hot flashes and night sweats by an average of 50%. At the end of the treatment period, significant improvements were found in: anxiety/fears; memory/concentration; menstrual problems; sexual behavior; sleep problems; somatic symptoms; and vasomotor symptoms. The authors state, “These results compare favorably with other studies using acupuncture to manage HF&NS, as well as research on nonhormonal pharmaceutical treatments. In addition to reduced HF&NS frequency, women enjoyed improved physical and emotional well-being, and few side-effects were reported.” 

Don’t Skip Your Breakfast!

Prior research suggests that breakfast eaters may be healthier than people who skip breakfast, and now a study in the American Journal of Clinical Nutrition suggests a nutritious breakfast may be especially good for your heart. Specifically, the recent study shows that regular breakfast eaters may reduce risk factors linked to heart disease.

Breakfast eaters reduce heart disease risk factors

While prior research has shown that skipping breakfast may lower a person’s energy level and increase the risk of weight gain, less is known about the effects of skipping breakfast on other body organs and functions.

In this study, 2,184 participants, 9 to 15 years old, initially filled out a questionnaire about diet and physical activity and stated whether they usually ate breakfast before school or not. Twenty years later, one third of the original participants filled out a meal frequency questionnaire, had their waist size measured, and had blood levels of triglycerides, total and LDL (“bad”) cholesterol, and fasting insulin (insulin levels after no food has been eaten overnight) checked. Participants were then classified into four groups:

• skipped breakfast in neither childhood nor adulthood,

• skipped breakfast only in childhood,

• skipped breakfast only in adulthood, or

• skipped breakfast in both childhood and adulthood.

Results showed that people who skipped breakfast in both childhood and adulthood had a larger waist size and total cholesterol and LDL cholesterol levels compared with people who ate breakfast in both childhood and adulthood. They also had higher fasting insulin levels, which indicates they have insulin resistance, a risk factor for diabetes and heart disease.

Breakfast skippers also tended to be single, have a lower education level, and were more likely to smoke, watch TV, get less physical activity, and have a less healthy diet compared with breakfast eaters.

The authors comment, “Skipping breakfast was associated with a larger waist circumference, cardiometabolic risk factors, poorer diet quality, and unhealthy lifestyle behaviors.” They add that promoting the benefits of eating breakfast may be an important public health message.

M
ore reasons to be a breakfast eater

There are many good reasons to eat breakfast, and prior research has shown that compared with breakfast skippers, breakfast eaters tend to have:

Better habits. People who eat breakfast tend to have healthier diets and get more physical activity.

A more nutritious diet. Breakfast eaters tend to eat less daily fat and cholesterol and more fiber, vitamins, and minerals.

A healthier weight. Some studies suggest that breakfast eaters have a lower weight compared with breakfast skippers.

Natural Remedies and Anxiety-A Summary

The October 7th, 2010 edition of Nutrition Journal published a summary of studies investigating nutritional and herbal treatments of anxiety. 71% of the studies (15 of 21) showed that the nutritional and herbal interventions were indeed effective in the treatment of anxiety. Specific supplements tested which showed positive results included those containing extracts of passionflower, kava, combinations of L-lysine and L-arginine. Supplementation with magnesium showed promise, while St. John’s wort was not found to be effective as an anti-anxiety treatment. Another benefit with these therapies, as opposed to pharmaceutical interventions, is that minimal side-effects were reported.

If you’re suffering from anxiety or other mood disorders, it’s definitely worth pursuing “alternative” forms of treatment, as the risk of becoming dependent on anti-anxiety medications is very high. Clinically, I’ve found a number of these treatments, along with acupuncture and other modalities, to be just as effective or better than pharmacological interventions for anxiety.

Collards, Carrots, and Breast Cancer

Researchers looking at data from the ongoing Black Women’s Health Study found that eating carrots, collard greens, cabbage, and broccoli can reduce breast cancer risk, particularly an aggressive form common among African American women. Previous studies of the relationship between fruit and vegetable consumption and breast cancer in white women have led to conflicting results, and no prior research has investigated this link separately among African American women.

The ER-negative form of breast cancer, which is insensitive to the hormone estrogen, is more common in this population than among white women. It is more difficult to treat and more often fatal than estrogen-sensitive cancers.

Researchers found that women who ate at least two servings of vegetables a day had a 43 percent lower risk of ER-negative breast cancer compared with women who ate fewer than four servings of vegetables each week.

Further, they identified certain types of vegetables that appeared to reduce the risk of all types of breast cancer, including broccoli, collard greens, cabbage and carrots.

Women who ate three or more servings a week of carrots, for instance, had a 17 percent lower risk of developing breast cancer than women who ate carrots less than once a month.

Still, it is too early to determine if this is a true cause-and effect-relationship, they note. High vegetable consumption could mark a healthier lifestyle in general or some other unknown mechanism that accounts for the apparent protection. Vegetables’ cancer-staving power needs to be confirmed in further studies, the researchers write. However, it is clear that, in addition to potential protective effects against breast cancer, higher vegetable consumption can lead to many health benefits, including lower risk of cardiovascular disease. Therefore, it is recommended that all women, especially African Americans, try to increase their daily intake of vegetables to meet the established guidelines.

Breast Cancer and HRT (Once Again)

We’ve known for several years that hormone replacement therapy (HRT) increases the risk of breast cancer.  Now, a new report derived from following the same population that was originally studied in the Women’s Health Initiative demonstrates even more risks associated with HRT.  The new findings showed that women who took Prempro (one of the main drugs prescribed for HRT) and developed breast cancer were more likely to have an aggressive form of the disease, and more likely to die than breast cancer patients who had never taken hormones.  One explanation for this is that HRT increases the density of breast tissue, making cancerous tumors harder to identify on mammogram and physical examination, delaying the diagnosis, and increasing the risk of death. For a more detailed article on the subject, visit:

http://www.nytimes.com/2010/10/20/health/20hormone.html?src=mv
Of course, there are plenty of alternatives to pharmaceutical HRT, so talk to your naturopathic doctor about safer options for managing menopausal symptoms and/or osteoporosis. 

High Glycemic Index and Inflammation

A recent study published in the American Journal of Clinical Nutrition (2010; 92(3): 634-43) further demonstrates the direct relationship between a high glycemic diet and inflammation. In a study involving 1490 postmenopausal women and 1245 men (baseline average age: 49 years) from a population-based cohort, women consuming a diet with the highest glycemic index (highest tertile) were found to have a 2.9-fold increased risk of inflammatory-disease related death, as compared to women in the lowest tertile of GI diet (multivariate HR=2.89). Increased intakes of foods high in refined sugars or starches and decreasing intake of vegetables other than potatoes as well as cereals and breads was also independently associated with a greater risk. The authors conclude, “These data provide new epidemiologic evidence of a potentially important link between GI and inflammatory disease mortality among older women.”

Artificial Sweeteners=Real Trouble

Most of my patients know that I’m not a fan of artificial sweeteners, but people often have      a hard time cutting them out of their diet. Hopefully this evidence (excerpted from   mercola.com) will be enough of a motivator!

Why Artificial Sweeteners Can be Detrimental to Your Waistline

The belief that eating artificially sweetened foods and drinking artificially sweetened beverages will help you to lose weight is a carefully orchestrated deception. So if you are still opting for sugar-free choices for this reason, you are being sorely misled.

For years now studies have shown that consuming artificial sweeteners breaks the connection between a sweet sensation and a high-calorie food, thereby changing your body’s ability to regulate intake naturally.

In one study by psychologists at Purdue University’s Ingestive Behavior Research Center, rats that ate yogurt sweetened with an artificial sweetener consumed more calories (and didn’t make up for it by cutting back later), gained more weight, and put on more body fat than rats that ate yogurt sweetened with sugar.

Other studies, too, have shown that eating artificial sweeteners might hinder your body’s ability to estimate calorie intake, thus boosting your inclination to overindulge. Your body and your brain simply do not have the same biological response to artificial sweeteners that they do to regular sugar, and this can pose some serious problems.

Your Brain Can Tell the Difference

You may have convinced yourself that your favorite artificial sweetener tastes the same as sugar, but rest assured your brain is not being fooled.

In one brain-scan study by neuroscientist Paul Smeets, volunteers were given two version of a beverage, one sweetened with sugar, the other with a blend of artificial sweeteners. The brain scans showed that the artificially sweetened beverage failed to activate an area of the brain called the caudate nucleus, which is an area associated with rewards.

A separate study by psychiatrist Guido Frank at the University of Colorado in Denver also looked into your brain’s response to sugar versus artificial sweeteners. Women given a taste of the two said they could not consciously determine a difference. However, a functional magnetic resonance imaging (fMRI) of their brain responses showed differences indeed.

As in the previously mentioned study, the sugar activated the reward areas of your brain more strongly than the artificial sweetener, suggesting that the latter may not make you feel satisfied the way sugar would.

This is not an endorsement to indulge in sugar; rather it’s a major clue that your body is not being fooled by artificial sweeteners.

High Fructose Corn Syrup Tries To Hide Behind Name Change

In an attempt to try and fool the public, the Corn Refiner’s Association has applied with the FDA to change the name of high fructose corn syrup to “corn sugar”. This would imply that high fructose corn syrup is a “natural” product, when in reality it is a highly synthetic product. The move may have partly been prompted by a recent Princeton University study demonstrating that rats who consumed high fructose corn syrup “gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same.”
For more information, visit the following website:

http://www.takepart.com/news/2010/09/14/high-fructose-corn-syrup-up-for-a-new-name?fb_js_fbu=757915220

Cognitive Impairment and B Vitamins

Daily tablets of large doses of vitamins can halve the rate of brain shrinkage in elderly people with memory problems and may slow their progression toward dementia, data from a recent British trial showed.

Scientists from Oxford University said their two-year clinical trial was the largest to date into the effect of B vitamins on so-called “mild cognitive impairment” — a major risk factor for Alzheimer’s disease and other forms of dementia.

Experts commenting on the findings said they were important and called for larger, longer full-scale clinical trials to see if the safety and effectiveness of B vitamins in the prevention of neurodegenerative conditions could be confirmed.

“This is a very dramatic and striking result. It’s much more than we could have predicted,” said David Smith of Oxford’s department of pharmacology, who co-led the trial.

“It is our hope that this simple and safe treatment will delay development of Alzheimer’s in many people who suffer from mild memory problems.”

Mild cognitive impairment (MCI) affects around 16 percent of people aged over 70 worldwide and is characterized by slight problems with memory loss, language or other mental functions.

MCI does not usually interfere with daily life, but around 50 percent of people diagnosed with it go on to develop the far more severe Alzheimer’s disease within five years. Alzheimer’s is a mind-wasting disease for which there are few treatments and no cure, and which affects 26 million people around the world.

Smith and colleagues conducted a two-year trial with 168 volunteers with MCI who were given either a vitamin pill containing very high doses of folic acid, vitamin B6 and vitamin B12, or a placebo dummy pill.

These B vitamins are known to control levels of an amino acid called homocysteine in the blood, and high blood levels of homocysteine are linked to an increased risk of developing Alzheimer’s disease.

Brain scans were taken at the beginning and the end of the trial to monitor the rate of brain shrinkage, or atrophy.

The results, published in the Public Library of Science (PLoS) One journal, showed that on average the brains of those taking the vitamin treatment shrank at a rate of 0.76 percent a year, while those taking the dummy pill had an average brain shrinkage of 1.08 percent.

People who had the highest levels of homocysteine at the start of the trial benefited the most from the treatment, with their brains shrinking at half the rate of those on the placebo.

Although the trial was not designed to measure cognitive ability, the researchers found those people who had lowest rates of shrinkage had the highest scores in mental tests.

Blueberries and Insulin

A new study published in the Journal of Nutrition (August 19, 2010) showed that subjects who consumed blueberries twice/day for 6 weeks had an improvement in insulin sensitivity. The participants were all obese and insulin-resistant, but not diabetic.

Blueberries have long been considered a “super-food” because of their high antioxidant and fiber content, and are often recommended for diabetic or insulin-resistant patients due to their negligible affect on blood sugar (as opposed to other fruits). However, the fact that they are now proven to actually reverse insulin-resistance makes it even more important for doctors to emphasize that all patients who are pre-diabetic and/or obese consume blueberries on a daily basis.

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