Natural Remedies and Anxiety-A Summary

The October 7th, 2010 edition of Nutrition Journal published a summary of studies investigating nutritional and herbal treatments of anxiety. 71% of the studies (15 of 21) showed that the nutritional and herbal interventions were indeed effective in the treatment of anxiety. Specific supplements tested which showed positive results included those containing extracts of passionflower, kava, combinations of L-lysine and L-arginine. Supplementation with magnesium showed promise, while St. John’s wort was not found to be effective as an anti-anxiety treatment. Another benefit with these therapies, as opposed to pharmaceutical interventions, is that minimal side-effects were reported.

If you’re suffering from anxiety or other mood disorders, it’s definitely worth pursuing “alternative” forms of treatment, as the risk of becoming dependent on anti-anxiety medications is very high. Clinically, I’ve found a number of these treatments, along with acupuncture and other modalities, to be just as effective or better than pharmacological interventions for anxiety.

Breast Cancer and HRT (Once Again)

We’ve known for several years that hormone replacement therapy (HRT) increases the risk of breast cancer.  Now, a new report derived from following the same population that was originally studied in the Women’s Health Initiative demonstrates even more risks associated with HRT.  The new findings showed that women who took Prempro (one of the main drugs prescribed for HRT) and developed breast cancer were more likely to have an aggressive form of the disease, and more likely to die than breast cancer patients who had never taken hormones.  One explanation for this is that HRT increases the density of breast tissue, making cancerous tumors harder to identify on mammogram and physical examination, delaying the diagnosis, and increasing the risk of death. For a more detailed article on the subject, visit:

http://www.nytimes.com/2010/10/20/health/20hormone.html?src=mv
Of course, there are plenty of alternatives to pharmaceutical HRT, so talk to your naturopathic doctor about safer options for managing menopausal symptoms and/or osteoporosis. 

High Glycemic Index and Inflammation

A recent study published in the American Journal of Clinical Nutrition (2010; 92(3): 634-43) further demonstrates the direct relationship between a high glycemic diet and inflammation. In a study involving 1490 postmenopausal women and 1245 men (baseline average age: 49 years) from a population-based cohort, women consuming a diet with the highest glycemic index (highest tertile) were found to have a 2.9-fold increased risk of inflammatory-disease related death, as compared to women in the lowest tertile of GI diet (multivariate HR=2.89). Increased intakes of foods high in refined sugars or starches and decreasing intake of vegetables other than potatoes as well as cereals and breads was also independently associated with a greater risk. The authors conclude, “These data provide new epidemiologic evidence of a potentially important link between GI and inflammatory disease mortality among older women.”

Artificial Sweeteners=Real Trouble

Most of my patients know that I’m not a fan of artificial sweeteners, but people often have      a hard time cutting them out of their diet. Hopefully this evidence (excerpted from   mercola.com) will be enough of a motivator!

Why Artificial Sweeteners Can be Detrimental to Your Waistline

The belief that eating artificially sweetened foods and drinking artificially sweetened beverages will help you to lose weight is a carefully orchestrated deception. So if you are still opting for sugar-free choices for this reason, you are being sorely misled.

For years now studies have shown that consuming artificial sweeteners breaks the connection between a sweet sensation and a high-calorie food, thereby changing your body’s ability to regulate intake naturally.

In one study by psychologists at Purdue University’s Ingestive Behavior Research Center, rats that ate yogurt sweetened with an artificial sweetener consumed more calories (and didn’t make up for it by cutting back later), gained more weight, and put on more body fat than rats that ate yogurt sweetened with sugar.

Other studies, too, have shown that eating artificial sweeteners might hinder your body’s ability to estimate calorie intake, thus boosting your inclination to overindulge. Your body and your brain simply do not have the same biological response to artificial sweeteners that they do to regular sugar, and this can pose some serious problems.

Your Brain Can Tell the Difference

You may have convinced yourself that your favorite artificial sweetener tastes the same as sugar, but rest assured your brain is not being fooled.

In one brain-scan study by neuroscientist Paul Smeets, volunteers were given two version of a beverage, one sweetened with sugar, the other with a blend of artificial sweeteners. The brain scans showed that the artificially sweetened beverage failed to activate an area of the brain called the caudate nucleus, which is an area associated with rewards.

A separate study by psychiatrist Guido Frank at the University of Colorado in Denver also looked into your brain’s response to sugar versus artificial sweeteners. Women given a taste of the two said they could not consciously determine a difference. However, a functional magnetic resonance imaging (fMRI) of their brain responses showed differences indeed.

As in the previously mentioned study, the sugar activated the reward areas of your brain more strongly than the artificial sweetener, suggesting that the latter may not make you feel satisfied the way sugar would.

This is not an endorsement to indulge in sugar; rather it’s a major clue that your body is not being fooled by artificial sweeteners.

High Fructose Corn Syrup Tries To Hide Behind Name Change

In an attempt to try and fool the public, the Corn Refiner’s Association has applied with the FDA to change the name of high fructose corn syrup to “corn sugar”. This would imply that high fructose corn syrup is a “natural” product, when in reality it is a highly synthetic product. The move may have partly been prompted by a recent Princeton University study demonstrating that rats who consumed high fructose corn syrup “gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same.”
For more information, visit the following website:

http://www.takepart.com/news/2010/09/14/high-fructose-corn-syrup-up-for-a-new-name?fb_js_fbu=757915220

Cognitive Impairment and B Vitamins

Daily tablets of large doses of vitamins can halve the rate of brain shrinkage in elderly people with memory problems and may slow their progression toward dementia, data from a recent British trial showed.

Scientists from Oxford University said their two-year clinical trial was the largest to date into the effect of B vitamins on so-called “mild cognitive impairment” — a major risk factor for Alzheimer’s disease and other forms of dementia.

Experts commenting on the findings said they were important and called for larger, longer full-scale clinical trials to see if the safety and effectiveness of B vitamins in the prevention of neurodegenerative conditions could be confirmed.

“This is a very dramatic and striking result. It’s much more than we could have predicted,” said David Smith of Oxford’s department of pharmacology, who co-led the trial.

“It is our hope that this simple and safe treatment will delay development of Alzheimer’s in many people who suffer from mild memory problems.”

Mild cognitive impairment (MCI) affects around 16 percent of people aged over 70 worldwide and is characterized by slight problems with memory loss, language or other mental functions.

MCI does not usually interfere with daily life, but around 50 percent of people diagnosed with it go on to develop the far more severe Alzheimer’s disease within five years. Alzheimer’s is a mind-wasting disease for which there are few treatments and no cure, and which affects 26 million people around the world.

Smith and colleagues conducted a two-year trial with 168 volunteers with MCI who were given either a vitamin pill containing very high doses of folic acid, vitamin B6 and vitamin B12, or a placebo dummy pill.

These B vitamins are known to control levels of an amino acid called homocysteine in the blood, and high blood levels of homocysteine are linked to an increased risk of developing Alzheimer’s disease.

Brain scans were taken at the beginning and the end of the trial to monitor the rate of brain shrinkage, or atrophy.

The results, published in the Public Library of Science (PLoS) One journal, showed that on average the brains of those taking the vitamin treatment shrank at a rate of 0.76 percent a year, while those taking the dummy pill had an average brain shrinkage of 1.08 percent.

People who had the highest levels of homocysteine at the start of the trial benefited the most from the treatment, with their brains shrinking at half the rate of those on the placebo.

Although the trial was not designed to measure cognitive ability, the researchers found those people who had lowest rates of shrinkage had the highest scores in mental tests.

Blueberries and Insulin

A new study published in the Journal of Nutrition (August 19, 2010) showed that subjects who consumed blueberries twice/day for 6 weeks had an improvement in insulin sensitivity. The participants were all obese and insulin-resistant, but not diabetic.

Blueberries have long been considered a “super-food” because of their high antioxidant and fiber content, and are often recommended for diabetic or insulin-resistant patients due to their negligible affect on blood sugar (as opposed to other fruits). However, the fact that they are now proven to actually reverse insulin-resistance makes it even more important for doctors to emphasize that all patients who are pre-diabetic and/or obese consume blueberries on a daily basis.

ADHD and Pesticides

More evidence has come about that links pesticide exposure with ADHD. The study, published in Environmental Health Perspectives, adds to evidence that organophosphatepesticides can affect the human brain. Researchers at the University of California Berkeley tested pregnant women for evidence that organophosphate pesticides had actually been absorbed by their bodies, and then followed their children as they grew. Women with more chemical traces of the pesticides in their urine while pregnant had children more likely to have symptoms of attention deficit hyperactivity disorder, or ADHD, at age 5, the researchers found.

Organophosphates are designed to attack the nervous systems of bugs by affecting message-carrying chemicals called neurotransmitters including acetylcholine, which is important to human brain development.

The researchers tested Mexican-American women living in the Salinas Valley of California, an area of intensive agriculture. They looked for breakdown products or metabolites from pesticides in urine samples from the mothers during pregnancy and from their children as they grew. A tenfold increase in pesticide metabolites in the mother’s urine correlated to a 500 percent increase in the chances of ADHD symptoms by age 5, with the trend stronger in boys.

In May a different team found children with high levels of organophosphate traces in the urine were almost twice as likely to develop ADHD as those with undetectable levels.

There are about 40 organophosphate pesticides such as malathion registered in the United States. Studies have also linked exposure to Parkinson’s, an incurable brain disease.

From a naturopathic perspectives, there are tests that can be performed to evaluate levels of organophosphates. This is not only important for children with ADHD, but also patients with any underlying neurological disease, as well as cancer. If identified, treatment protocols to facilitate pesticide detoxification (using natural substances) can be utilized.

Heart Disease and Anxiety

The July issue of the Archives of General Psychiatry contains a study that demonstrates a 74% increased risk for adverse cardiovascular events (stroke, heart attack, and sudden death) in patients with general anxiety disorder (GAD). While it’s often been speculated that many patients with coronary heart disease (CHD) are also anxious, this study is the first of it’s kind to prove that there is indeed a definitive link between anxiety and heart disease. 

This study is further proof that the mind-body connection cannot be ignored. If your stress level is consistently high, don’t wait until you begin to experience symptoms before taking the necessary steps to address your anxiety. Naturopathic medicine can offer a number of therapies, including botanical, nutritional, acupuncture, and biofeedback, to help you manage stress more effectively. The Heart Math Institute (www.heartmath.org) offers tips and products that help you “retrain” your stress response, making you less prone to the adverse effects of anxiety. MoodGym (http://moodgym.anu.edu.au/welcome) is another online resource that is recommended for this purpose. 

Weight Loss and Natural Medicine

Naturopathic Medicine can offer a number of options for helping people to lose weight. From hormonal imbalances to underlying food allergies, the causes of abnormal weight gain are varied, so it’s important to seek an individualized approach to losing weight. Consulting an experienced naturopath will help you identify obstacles to weight loss, allowing you to lose weight in a safe, medically supervised fashion.

In the meantime, here are some general tips to help you lose or maintain your weight:

Talk with a professional. Being overweight increases a person’s risk of a number of medical conditions such as type 2 diabetes, high blood pressure, and high cholesterol. If you are overweight, talk with a knowledgeable doctor to come up with a good program for you, and work with a nutritionist who can educate you about what to eat and help you stay motivated and on track for a healthy weight. As this study showed, people who attended more dietary counseling sessions lost greater amounts of weight than those who attended less.

Identify triggers that lead to cravings or overeating. It is important to ask yourself questions such as “Why do I choose foods that are not healthy for me?” and “What feelings or circumstances lead me to crave unhealthy foods or to overeat?” Answering such questions can help you learn how to manage the cravings and feelings that lead to overeating, and help you plan ahead with healthier alternatives in situations where you might normally make unhealthy choices.

Choose the right foods. You know the recommendations by now, but have you taken specific steps to improve your diet? The body needs an abundance of fruits and veggies–at least 5 servings every day–and a source of protein every day in order to optimize health and prevent disease. Eating foods high in sugar increases cravings, so reach for low-sugar, low-fat, nutrient-dense foods when eating regular meals and when snacking.

Plan ahead. Sit down and plan your meals for the week. Try grocery shopping on a Sunday in order to stock the refrigerator with healthy foods to get you through the week. Don’t bring high-sugar, high-fat foods into the house, which may increase the temptation for overeating, but keep looking for healthy foods that you really enjoy so you have options if a snack attack hits.

Exercise regularly. Guidelines recommend 60 minutes of exercise every day for healthy adults and 90 minutes for children. Exercise helps reduce cravings and overeating and also improves risk factors for chronic disease such as high blood pressure, glucose and cholesterol levels. If the optimal amount is too overwhelming either because of your schedule or fitness level, remember that everything helps. Get the all-clear from your doctor, and then start slowly and build over time. As your fitness improves, you will naturally enjoy longer exercise sessions, rather than slogging through. Exercise buddies and cross-training are also good tricks for keeping yourself going.

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